WEBVTT

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3 billion letters. In every one of them, a possible answer. But a single change, hidden

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among millions, can alter an entire life. Finding it takes weeks, and Folklore changes that.

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An entire genome, annotated and classified in under 10 minutes. It only takes less than

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10 minutes to annotate every variant, and to classify it against the international ACMG

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standard. Folklore matches the variants to the patient's clinical picture, connects the

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evidence from the literature, and surfaces what matters, transparent at every step. Each

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finding opens directly in Folklore's genome browser. The geneticist can move through the

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genome, zoom into the surrounding region, and see how that variant relates to nearby

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genes, other variants, and the evidence behind its classification. Folklore compares the patient's

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clinical picture with the genetic findings. It ranks the variants by how closely they match

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the suspected diagnosis, bringing the most relevant findings to the top. The geneticist

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can focus first on the variants that best fit the patient.

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Folklore's AI assistant is central to the clinical interpretation workflow. Across the

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platform, it works with the complete case already in context, the patient's clinical

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picture, the detected variants, and the evidence behind each one. The geneticist can ask which

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variants best explain the case, how they relate to the patient's symptoms, and what

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deserves review next.

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In seconds, Folklore delivers a focused interpretation and brings the most relevant results to the

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front. One model for the real complexity of rare disease. A single patient, an entire

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family, or a whole cohort. Folklore brings the genome, the clinical picture, and the

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evidence into one place. Developed with diagnostic laboratories and tested on real

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clinical cases, it helps the geneticist focus on what matters and decide faster.

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Folklore reads the evidence, the geneticist decides.