Variant evidence review
Treat unsupported scope as an explicit result
Folklore Clinical Variant Interpretation MCP supports public GRCh38 germline nuclear SNVs and simple indels smaller than 50 bp. Structural, mitochondrial, GRCh37 and batch workflows remain outside this public interface.
Agent question
Does this public variant fall inside the current MCP input contract?
Check scope before calling
Confirm assembly, nuclear or mitochondrial context, variant type and request size. Do not silently lift over, decompose or substitute an unsupported input.
- GRCh38 only
- Nuclear germline SNV or simple indel
- One public variant per call
- No structural or mitochondrial variant
- No VCF or batch upload
Product scope is not MCP scope
Folklore product capabilities outside this public interface do not authorize an agent to claim that the MCP contract supports the same inputs. Report the published interface boundary exactly.
Public references
Clinical and data boundary
Folklore Clinical Variant Interpretation MCP is published by Helena Bioinformatics. It accepts public variant-level queries only, not patient, phenotype, family, segregation or private case data. Its results are automated decision support for qualified professional review, not a diagnosis or treatment recommendation.