Product overview

Folklore in 2 minutes

See how Folklore connects genome annotation, variant classification, phenotype matching and a case-aware AI assistant for geneticist review.

2:27 / Product overview

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Video transcript

Edited transcript of the published product overview. Timing statements describe the demonstrated workflow; processing time depends on the input and configuration. Interpretation remains subject to qualified professional review.

3 billion letters. In every one of them, a possible answer. But a single change, hidden among millions, can alter an entire life.

Finding it takes weeks, and Folklore changes that. An entire genome, annotated and classified in under 10 minutes. It only takes less than 10 minutes to annotate every variant, and to classify it against the international ACMG standard.

Folklore matches the variants to the patient's clinical picture, connects the evidence from the literature, and surfaces what matters, transparent at every step. Each finding opens directly in Folklore's genome browser. The geneticist can move through the genome, zoom into the surrounding region, and see how that variant relates to nearby genes, other variants, and the evidence behind its classification.

Folklore compares the patient's clinical picture with the genetic findings. It ranks the variants by how closely they match the suspected diagnosis, bringing the most relevant findings to the top. The geneticist can focus first on the variants that best fit the patient.

Folklore's AI assistant is central to the clinical interpretation workflow. Across the platform, it works with the complete case already in context, the patient's clinical picture, the detected variants, and the evidence behind each one. The geneticist can ask which variants best explain the case, how they relate to the patient's symptoms, and what deserves review next.

In seconds, Folklore delivers a focused interpretation and brings the most relevant results to the front. One model for the real complexity of rare disease. A single patient, an entire family, or a whole cohort.

Folklore brings the genome, the clinical picture, and the evidence into one place. Developed with diagnostic laboratories and tested on real clinical cases, it helps the geneticist focus on what matters and decide faster. Folklore reads the evidence, the geneticist decides.